Author: huzefakifayet

PHENINDAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

  Phenindamine              IUPAC nomenclature 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridine   Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 261.4 g/mol 2 Physical appearance Solid 3 Melting point 91oC 4 Solubility 2.77e-02 g/L 5 Octanol/water […]

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CHLORCYCLIZINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Chlorcyclizine IUPAC nomenclature 1-[(4-Chlorophenyl)(phenyl)methyl]-4-methylpiperazine Classification H1-receptor antihistamine Piperazine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 300.8g/mol 2 Physical appearance Oil 3 Melting point 216oC 4 Solubility Water solubility is 0.0424 mg/ml 5 Octanol/water partition […]

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HYDROXYZINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Hydroxyzine IUPAC nomenclature (±)-2-(2-{4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl}ethoxy)ethanol Classification H1-receptor antihistamine Piperazine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 374.9 g/mol 2 Physical appearance Solid or oil 3 Melting point 190oC 4 Solubility 428 mg/L in water 5 […]

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PROMETHAZINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Promethazine IUPAC nomenclature N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine Classification H1-receptor antihistamine Phenothiazine derivative antihistamine drug   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 284.4 g/mol 2 Physical appearance White to faint yellow crystalline powder 3 Melting point 60oC 4 Solubility […]

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