The post STERILIZATION, Needs, Methods and Types of Sterilization, Sterility testing, MCQs appeared first on Gpatindia: Pharmacy Jobs, Admissions, Scholarships, Conference,Grants, Exam Alerts.
]]>Sterilization is the either killing or removal of all the microorganisms from an object to make it free from any living organism. It also includes killing or removal of bacterial endospores and fungal endospores which are highly resistant in nature. [1]
All the pharmaceutical equipments, used for medical, parentral and ophthalmic preparations are mandatory to be sterilized prior to its use. They are usually sterilized using heat method. Prefilled syringes and ophthalmic preparations are sterilized using ethylene oxide and irradiation method. For small and large parentral devices and for opthamic products sterilization, moist heat sterilization method is used.
I. Physical methods: The physical methods for sterilization includes:
II. Chemical methods: In this, various chemicals are used for sterilization.
III. Mechanical methods: This includes filtration for sterilization.
Sterilization is very important process. There are some tests which can be used for the evaluation of the sterilization process. The basic principle behind the tests for sterility is that, whenever a microorganism is provided with a nutrient medium, suitable temperature and pressure, it grows and multiples, which can be visible as a turbidity or as a colony on the culture media.
Methods which can be used for the sterility tests:
I. Direct inoculation method
II. Membrane filtration method
III. Pyrogen test
a. Process of growing microbes in laboratory
b. Process for preparation of antibiotics
c. Killing or removing of all the microorganisms from an article
d. Fragmentation of big particles into smaller one for the preparation of tablets
2. Which of the following method is used for sterilization?
a. Moist heat method
b. Staining
c. Microbial inoculation
d. Incubation
3. Parenteral preparations can be sterilized through?
a. Chemical sterilization
b. Membrane filtration
c. Desiccation
d. Dry heat method
4. Basic principle behind sterility testing is?
a. Microorganisms imparts different colors when present as contaminant in any preparation
b. Presence of microbes can be detected by naked eye in any preparation
c. Microbes will grow if they will be provided with nutrient medium, optimum temperature and pH
d. None of the above
5. Correct sequence of true/false for the following staments can be?
a. TFFT
b. FFTT
c. FFFT
d. FTFT
6. Which of the following statements are correct?
I. Pasteurization kills pathogens present in milk
II. Chemical cannot be used for sterilization purpose
III. Pyrogen test can be used for the test of sterility
IV. Radiations can be used for sterilization
a. I, III, IV
b. II, IV
c. III
d. I, II, III
7. Which of the following comes under physical method of sterilization?
I. Moist heat method
II. Oxidation
III. Sunlight
IV. Osmotic pressure
V. Lyophillization
VI. Ethylene oxide treatment
a. III, IV, VI
b. I, III, IV, V
c. I, V
d. II, IV, VI
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1-c
2-a
3-b
4-c
5-d
6-a
7-d
The post STERILIZATION, Needs, Methods and Types of Sterilization, Sterility testing, MCQs appeared first on Gpatindia: Pharmacy Jobs, Admissions, Scholarships, Conference,Grants, Exam Alerts.
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