MCQ on Antimalarial Drug Quinine | Important for Competitive exams of Medical, Pharmacy, Nursing, Physiotherapy and Dental
1. Quinine is primarily used for the treatment of which disease?
A. Tuberculosis
B. Malaria
C. Typhoid
D. Leprosy
Answer: B. Malaria
2. Quinine is obtained from which natural source?
A. Opium poppy
B. Cinchona bark
C. Digitalis leaves
D. Tea leaves
Answer: B. Cinchona bark
3. Which species of Plasmodium is quinine particularly effective against?
A. Plasmodium vivax
B. Plasmodium malariae
C. Plasmodium falciparum
D. Plasmodium ovale
Answer: C. Plasmodium falciparum
4. Quinine belongs to which class of chemical compounds?
A. Alkaloids
B. Steroids
C. Flavonoids
D. Polysaccharides
Answer: A. Alkaloids
5. What is a common side effect associated with quinine therapy?
A. Hypertension
B. Quinine blindness
C. Cinchonism
D. Bradycardia
Answer: C. Cinchonism
6. Which of the following symptoms is not associated with cinchonism?
A. Tinnitus
B. Headache
C. Nausea
D. Rash
Answer: D. Rash
7. What is the mechanism of action of quinine?
A. Inhibits bacterial cell wall synthesis
B. Interferes with DNA replication
C. Inhibits heme polymerase in the malaria parasite
D. Blocks folic acid synthesis
Answer: C. Inhibits heme polymerase in the malaria parasite
8. Quinine should be used with caution in patients with which condition?
A. Diabetes mellitus
B. Asthma
C. G6PD deficiency
D. Hypertension
Answer: C. G6PD deficiency
9. Which of the following is a synthetic analog of quinine used in malaria treatment?
A. Metronidazole
B. Chloroquine
C. Ivermectin
D. Ciprofloxacin
Answer: B. Chloroquine
10. Which statement about quinine is false?
A. It is effective against liver stages of malaria.
B. It is used in combination therapy in drug-resistant malaria.
C. It has antipyretic and analgesic properties.
D. It is classified as a bitter-tasting compound.
Answer: A. It is effective against liver stages of malaria.