MCQs on Anticancer Drugs

MCQs on Anticancer Drugs

Q1. Which of the following is a purine analog?
A. Methotrexate
B. 6-Mercaptopurine
C. 5-Fluorouracil
D. Cyclophosphamide
✅ Answer: B

Q2. Paclitaxel acts by:
A. Inhibiting DNA synthesis
B. Stabilizing microtubules
C. Inhibiting thymidylate synthase
D. Alkylating DNA
✅ Answer: B

Q3. Which drug is a monoclonal antibody targeting HER2/neu?
A. Bevacizumab
B. Rituximab
C. Trastuzumab
D. Cetuximab
✅ Answer: C

Q4. Leucovorin is used as a rescue agent with:
A. Cyclophosphamide
B. Methotrexate
C. 5-Fluorouracil
D. Bleomycin
✅ Answer: B

Q5. Bleomycin’s dose-limiting toxicity is:
A. Myelosuppression
B. Nephrotoxicity
C. Pulmonary fibrosis
D. Cardiotoxicity
✅ Answer: C

Q6. Which of the following is a topoisomerase II inhibitor?
A. Irinotecan
B. Topotecan
C. Etoposide
D. Vinblastine
✅ Answer: C