Classification of Anthelmintic Drugs and MCQ for NEETPG, GPAT, Nursing and Pharmacy Exams

Anthelmintics
│
├── 1. Benzimidazoles
│ ├── Albendazole
│ ├── Mebendazole
│ └── Thiabendazole
│
├── 2. Imidazothiazoles
│ └── Levamisole
│
├── 3. Tetrahydropyrimidines
│ └── Pyrantel pamoate
│
├── 4. Macrocyclic Lactones (Avermectins & Milbemycins)
│ └── Ivermectin
│
├── 5. Salicylanilides & Substituted Phenols
│ └── Niclosamide
│
├── 6. Isoquinoline-pyrazine Derivatives
│ └── Praziquantel
│
├── 7. Organophosphates
│ └── Dichlorvos (DDVP)
│
└── 8. Others
├── Piperazine (GABA agonist)
├── Diethylcarbamazine (DEC)
└── Bithionol (for Fascioliasis)

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Classification Based on Parasite Type

A. For Nematodes (Roundworms)
– Albendazole
– Mebendazole
– Levamisole
– Pyrantel
– Ivermectin
– Piperazine

B. For Cestodes (Tapeworms)
– Niclosamide
– Praziquantel
– Albendazole (in cysticercosis)

C. For Trematodes (Flukes)
– Praziquantel
– Bithionol
– Triclabendazole

MCQs on Anthelmintic Drugs

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1. Which drug is commonly used to treat schistosomiasis?
   • A) Albendazole
   • B) Praziquantel
   • C) Ivermectin
   • D) Piperazine
   • Answer: B
2. What is the primary mechanism of action of Benzimidazoles?
   • A) GABA agonist activity
   • B) Inhibition of microtubule polymerization
   • C) Binding to chloride channels
   • D) Increasing calcium permeability
   • Answer: B
3. Which anthelmintic drug is effective against filariasis?
   • A) Niclosamide
   • B) Diethylcarbamazine
   • C) Mebendazole
   • D) Pyrantel Pamoate
   • Answer: B
4. Which of the following drugs causes spastic paralysis in worms?
   • A) Thiabendazole
   • B) Pyrantel Pamoate
   • C) Praziquantel
   • D) Ivermectin
   • Answer: B
5. Niclosamide is primarily used to treat which type of infection?
   • A) Roundworm
   • B) Tapeworm
   • C) Fluke
   • D) Hookworm
   • Answer: B