Tag: NAFARELIN SAR

NAFARELIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Nafarelin IUPAC nomenclature (2R)-N-[(2R)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[(2R)-2-[(2R)-2-[(2R)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2R)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-(naphthalen-2-yl)propanamido]-4-methylpentanamide.   Classification Nafarelin is a GnRH analogue. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 1322.5 g/mol 2 Appearance White to off white solid 3 Melting point More than 181°C 4 Solubility […]

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