Notes on Mechanism of Action of Tetracyclines, Aminoglycosides, and Macrolides, and MCQ for NEET PG, GPAT and NORCET Exams
1. TETRACYCLINES Target: 30S ribosomal subunit of bacteria. Action: Tetracyclines bind reversibly to the 30S subunit. They block the attachment of aminoacyl-tRNA to the mRNA-ribosome complex. This prevents addition of new amino acids to the growing peptide chain → Stops […]