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Success of International Conclave on Ethical Leadership at IIHMR University Jan 2020

IIHMR University Hosted Big Event on Ethical Leadership 50 American Delegates attended the International Conclave on Ethical Leadership at IIHMR University  International Yoga Expert from Florida, Gurudev Shri Amritji and Shri. Kamini Devi were the master trainers  Principal Director of […]

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MSc Bioinformatics, Microbiology Admission 2020 at Banaras Hindu University(BHU), Varanasi

Admission open for Post Graduate Courses Life sciences at BHU Varanasi Name of Entrance Test: PET 2020 Courses Master of Science (MSc) Forensic Science Bioinformatics Applied Microbiology Botany Zoology Physics Chemistry 1. Requirement of Aadhaar for the Applicants 2.Following is […]

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ACTINOMYCIN D Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Actinomycin D (Dactinomycin) IUPAC nomenclature 2-Amino-N,N′- bis[(6S,9R,10S,13R,18aS)-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide. Classification Actinomycin D falls under the category of Antibiotic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 1255.4g/mol 2 Appearance Bright red rhomboid prisms / red powder […]

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DAUNORUBICIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Daunorubicin IUPAC nomenclature (8S,10S)-8-Acetyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione. Classification Duanorubicin falls under the category of Anthracyclic antibiotic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 527.5 g/mol 2 Appearance Thin red needle form 3 Melting point 208.5°C 4 […]

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MITOXANTRON Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Mitoxantron IUPAC nomenclature 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]-anthracene-9,10-dione. Classification Mitoxantron falls under the category of antibiotic Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 444.5g/mol 2 Appearance Present in liquid state. Can be obtained as blue-black solid […]

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BLEOMYCINS Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Bleomycins IUPAC nomenclature (3-{[(2′-{(5S,8S,9S,10R,13S)-15-{6-amino-2- [(1S)-3-amino-1-{[(2S)-2,3-diamino-3-oxopropyl]amino}-3-oxopropyl] -5-methylpyrimidin-4-yl}-13-[{[(2R,3S,4S,5S,6S)-3- {[(2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy} -4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy} (1H-imidazol-5-yl)methyl]-9-hydroxy-5-[(1R)-1-hydroxyethyl]-8,10-dimethyl-4,7,12,15-tetraoxo-3,6,11,14-tetraazapentadec-1-yl}-2,4′-bi-1,3-thiazol-4-yl)carbonyl]amino}propyl)(dimethyl)sulfonium. Classification Bleomycin falls under the category of antibiotic Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 1415.6 g/mol 2 Appearance Yellow to colorless […]

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MITOMYCIN C Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Mitomycin C IUPAC nomenclature {11-Amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl}methyl carbamate. Classification Mitomycin C falls under the category of antibiotic Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 334.33 g/mol 2 Appearance Blue-violet crystal form 3 Melting point […]

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ETOPOSIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Etoposide IUPAC nomenclature 4′-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside], 4′ -(dihydrogen phosphate). Classification Etoposide falls under the category of epipodophyllo toxin cytotoxic drug.   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 588.6 g/mol 2 Appearance Present in solid form; crystal […]

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