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Training Programme on Chromatography and Mass Spectrometry (only for Women) Free of Cost at NCL, Pune

SDP_NCL35 – Chromatography and Mass Spectrometry (only for Women) Overview The course is organized to encourage the active participation of woman in science for their empowerment. The specially designed course is very much essential for the identification and characterization of […]

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FINASTERIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Finasteride IUPAC nomenclature (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide.   Classification Finasteride is a 5-α reductase inhibitor. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 372.5g/mol 2 Appearance Fine white to off white crystalline solid 3 Melting point 252-254°C 4 Solubility […]

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DUTASTERIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Dutasteride IUPAC nomenclature (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide. Classification Dutasteride is a 5-α reductase inhibitor. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 528.5 g/mol 2 Appearance Solid 3 Melting point 242-250°C 4 Solubility Insoluble 5 Octanol/water partition coefficient 6.8 […]

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NAFARELIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Nafarelin IUPAC nomenclature (2R)-N-[(2R)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[(2R)-2-[(2R)-2-[(2R)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2R)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-(naphthalen-2-yl)propanamido]-4-methylpentanamide.   Classification Nafarelin is a GnRH analogue. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 1322.5 g/mol 2 Appearance White to off white solid 3 Melting point More than 181°C 4 Solubility […]

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Squill: Biological sources,Morphological features, MCQs and Medicinal Uses

SQUILL 1. Biological sources: • The botanical name of squill is Drimia maritima. • The biological source of squill is dried slices of bulb urginea indica kunth. • It is also known as urginea, scillae bulbus, scilla bulb, white squill […]

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BICALUTAMIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Bicalutamide IUPAC nomenclature (RS)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide.   Classification Bicalutamide is an antiandrogen. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 430.4 g/mol 2 Appearance Fine white to off white powder 3 Melting point 191-193°C 4 Solubility Soluble in […]

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