APPLICATIONS OF DIFFUSION PRINCIPLES: Drug Absorption by Passive Diffusion – Passive diffusion is the major trans-membrane transport process for most drugs. The driving force for passive diffusion is the difference in drug concentrations on either side of the cell membrane. […]
IN VITRO–IN VIVO CORRELATION: IVIVC refers to a relationship between a physicochemical characteristic of the dosage form, as determined by in vitro dissolution and biological property and as determined by in vivo pharmacokinetics. The objectives of IVIVC are to use […]
Any dissolution test method involves immersing the dosage form in a suitable dissolution medium, which is kept in motion at a constant speed and requires determining the rate at which the drug substance is released from the dosage form and […]
Systems of solids in liquids include the most frequently encountered and probably the most important type of pharmaceutical solutions. Many important drugs belong to the class of weak acids and bases. They react with strong acids and bases and, within […]
Effect of Ionic Dissociation and Molecular Association on Partition: The solute can exist partly or wholly as associated molecules in one of the phases or it may dissociate into ions in either of the liquid phases. The distribution law applies […]
PEPTIC ULER: Peptic ulcer are open sores that develop on the inner lining of the stomach and the upper portion of small intestine. It occurs in that part of the g.i.t which is exposed to gastric acid secretions. Types of […]
Bronchial Asthma: It is chronic condition in which a person’s airways become inflamed swell, narrow and produce extra mucus which make difficulty in breathing. Sign and symptoms: Coughing, shortness of breath, chest tightness and wheezing sound (whistling sound in airways). […]