Tag: DUTASTERIDE synthesis

DUTASTERIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Dutasteride IUPAC nomenclature (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide. Classification Dutasteride is a 5-α reductase inhibitor. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 528.5 g/mol 2 Appearance Solid 3 Melting point 242-250°C 4 Solubility Insoluble 5 Octanol/water partition coefficient 6.8 […]

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