Tag: topotecan mode of action

TOPOTECAN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Topotecan IUPAC nomenclature (S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride. Classification Toptecan falls under the category of camptothecin cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 421.4 g/mol 2 Appearance Present in solid form 3 Melting point Range between […]

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