Phenytoin IUPAC nomenclature 5,5-diphenylimidazolidine-2,4-dione. Classification Phenytoin is a hydantoin derivative anticonvulsant drug. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 252.27 g/mol 2 Physical appearance White crystalline powder 3 Melting point 296.5°C 4 Solubility Insoluble in […]
Electro analytical methods are concerned with the interplay between electrictiy and chemistry, namely the measurements of electrical quantities, such as current, potential, or/and their relationship to chemical parameters. If electrical parameter : E-Potentionmetry , R-conductometry, I- voltametry,coulometry MAIN BRANCHES OF ELECTROANALYTICAL […]
PRINCIPLE:- It is based on the principle of polarography , with the exception that the voltage is maintained constant during the titration. Diffusion current ∝ concentration of electroredusible ion Potential applied between polarizable & non polarizable is kept constant. INSTRUMENTATION:- Dropping […]
PROCEDURE OF HPLC:- The sample is introduced through an injection system into the entrance to the column. The stationary phase is porous silica. mobile phase can either be aqueous or organic solvent In interaction between mobile and stationary phase, two […]
INSTRUMENTATION OF HPLC :- HPLC INSTRUMENT CONSISTS OF FOLLOWING COMPONENTS:- PUMP MIXING UNIT SOLVENT DELIVERY SYSTEM INJECTOR COLUMN DETECTOR PUMP:- The role of the pump is to force a liquid through the liquid chromatography at a specific flow rate expressed […]
INTODUCTION :- High perfomance liquid chromatography is a specific form of a column chromatography generally used in bio chemistry and analysis to separate, identify and quantify the active compound. PRINCIPLE :- HPLC is principle is based on adsorption as well […]
Column characteristics :- The length: diameter ratio of column is 10:1 to 30:1. The length of the column is depend upon Affinity of compound towards the adsorbent used. Number of compound to be separated. Type of adsorbent used. Quantity of […]
Introduction :- Column Chromatography is a method of analysis in which the stationary phase is allowed to migrate across the surface of the column. The column is simply a glass tube with a stopcock at the bottom. The column is […]
Cell is a device which convert chemical energy into electrical energy. cell is consists of two half cell. ELECTRODE POTENTIAL:– Difference between the potential of two electrodes. POTENTIOMETRY consists of measuring potential or emf of solution using set of indicator & […]
REFERENCE ELECTRODES :- 2. SATURATED CALOMEL ELECTRODES:- It is consists of an inner jacket and outer sleeve. Inner tube has wire contact with mercury and plugged with a mixture of calomel and KCL. Outer sleeve is filled with saturated KCL […]