A number of anatomical and physiological factors determine the pharmacokinetic profile of a drug. Differences in physiology in paediatric populations compared with adults can influence the concentration of drug within the plasma or tissue. Healthcare professionals need to be aware […]
Adverse drug reactions (ADRs) are an important and frequent cause of morbidity and mortality. ADR can be related to a variety of drugs, including anticonvulsants, anaesthetics, antibiotics, antiretroviral, anticancer, and antiarrhythmics, and can involve every organ or apparatus. The causes […]
During pregnancy, a large part of the body is affected by the physiological and anatomical changes that start in early pregnancy. Many of these changes significantly affect the pharmacokinetic (absorption, distribution, metabolism, and excretion) and pharmacodynamic properties of different drugs […]
Elderly patients are the main users of drugs and they difer from younger patients. They are a heterogeneous population that cannot be defned only by age but should rather be stratifed based on their frailty. The elderly have distinctive pharmacokinetic […]
CDSCO Introduction The Central Drugs Standard Control Organization (CDSCO) is the Central Drug Authority for discharging functions assigned to the Central Government under the Drugs and Cosmetics Act. CDSCO has six zonal offices, four sub-zonal offices, 13 port offices and […]
Diploma in Pharmacy Exit Examination Regulations Objective The objective of the Diploma in Pharmacy Exit Examination (DPEE) is to ensure that a candidate applying for registration as pharmacist with the State Pharmacy Council has undergone pharmacy education and a comprehensive […]
Pharmacovigilance in India Indian pharmaceutical industries are estimated to account for about 3.5% in value of the international pharmaceutical industry. By 2020, it is expected to grow to US$55 billion and US$100 billion by 2025, thus evolving as the sixth […]
CIOMS: The Council for International Organizations of Medical Sciences (CIOMS) is an international, non-governmental, non-profit organization established jointly by WHO and UNESCO in 1949. CIOMS represents a substantial proportion of the biomedical scientific community through its member organizations, which include […]
ICH ICSR E2B R3 Guideline The ICH E2B EWG released an E2B guideline for Maintenance of the ICH Guideline on Clinical Safety Data Management: Data Elements for Transmission of Individual Case Safety Reports (ICSR) in 1997 and issued a revised […]