Pharmaceutical Aerosols Applications: They are used for their local action in the nasal areas, throat, and lungs, as well as for prompt systemic effect when absorbed from the lungs into the bloodstream (inhalation therapy). They are intended for topical application […]
Packaging methods: Two methods have been used to package aerosol products. Unlike non-aerosol products, part of the manufacturing of necessity takes place during the filling operation. The propellant and product concentrate must be brought together in a way that ensures […]
Aerosol formulation: Topical pharmaceuticals may be formulated as aerosols using solutions, suspensions, emulsions, powders, and semisolid preparations, while MDIs are formulated as solutions or suspensions. Solution aerosols – Topical aerosols consist of a solution of active ingredients in pure propellant […]
Pharmaceutical Aerosols The propellant generally is regarded as the heart of the aerosol package. In addition to supplying the necessary force to expel the product, the propellant must also act as a solvent and diluent and has much to do […]
Sterile powders: Dry sterile powder is aseptically added to a sterile vial. The dry drug powder is reconstituted with a sterile vehicle before use. Powders for injections are solid substances, distributed in their final containers and which, when shaken with […]
Quality Assurance and Control: The importance of undertaking every possible means to ensure the quality of the finished product cannot be overemphasized. Every component and step of the manufacturing process must be subjected to intense scrutiny to be confident quality […]
Containers and Closures: Injectable formulations are packaged into containers made of glass or plastic. Container systems include ampoules, vials, syringes, cartridges, bottles, and bags. Ampoules are all glass, whereas bags are all plastic. The other containers can be composed of […]