Folate Deficiency Anemia: Definition, Causes, Symptoms, Treatment and MCQs for NEET, GPAT, CSIR NET JRF
“A deficiency of folic acid, more properly pteroyl-monoglutamic acid, results in a megaloblastic anaemia having the same characteristics as those encountered in vitamin B-12 deficiency.”
1.] Women are at high risk of having Folate deficiency anaemia.
CAUSES: –
Following are the causes of Folate deficiency anaemia:
- Poor dietary intake
- Malabsorption
- Excess folate utilisation
- Pregnancy
- Chronic alcoholism
- Excess urinary folate loss
- Malignancy
SYMPTOMS: –
Following are the symptoms of Folate deficiency anaemia:
- Palpitation
- Breathlessness
- Weakness
- Pale skin due to anaemia
- Extreme tiredness
- Lethargy
- Feeling faint
- Headache
TREATMENT: –
Following is the medication given in the treatment of Folate deficiency anaemia:
1.] Oral folate, 1 mg daily for 4 months, is usually sufficient for treatment of folic
acid–deficiency anaemia, unless the etiology cannot be corrected. If malabsorption is
present, a dose of 1 to 5 mg daily may be necessary.
MULTIPLE CHOICE QUESTIONS: –
1.] Anemia with is cause due to the deficiency of folic acid is called?
a. Haemolytic anaemia
b. Folate deficiency anaemia
c. Both (a) and (b)
d. None of the above
2.] Folate deficiency anaemia is caused due to the deficiency of?
a. Folic acid
b. Vitamin A
c. Only (b)
d. None of the above
3.] Folate deficiency anaemia is a type of?
a. Haemolytic anaemia
b. Only (a)
c. Megaloblastic anaemia
d. None of the above
4.] Folic acid is a?
a. Vitamin B
b. Form of vitamin C
c. Substitute of vitamin E
d. Mineral
5.] Folic acid reduces the risk of?
a. Spina bifida
b. Anencephaly
c. All of the above
6.] Megaloblastic anaemia is seen in all except?
a. Hereditary TC I deficiency
b. TC II deficiency
c. Orotic aciduria
d. Imerslund Grasbeck disease
7.] Folic acid supplementation reduces the risk of stroke by?
a. 4%
b. 8%
c. 18%
d. 25%
8.] What is the most common cause of anaemia?
a. Too little sleep
b. Too much sugar
c. Too little iron in blood
d. Exposure to X-ray radiation
9.] Which of this age group is most likely to have anaemia?
a. Men
b. Women
c. Teenagers
d. Older adults
10.] Which of this are the signs of anaemia?
a. Pale gum
b. Dark circles under eyes
c. Bleeding
d. Numbness in hands and feet
SOLUTIONS: –
1.] (b) Folate deficiency anaemia
2.] (a) Folic acid
3.] (c) Megaloblastic anaemia
4.] (a) Vitamin B
5.] (c)
6.] (a) Hereditary TC I deficiency
7.] (c) 18%
8.] (c) Too little iron in blood
9.] (b) Women
10.] (a) Pale gum
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REFERENCES: –
1.] Textbook of Pathology by Harsh Mohan; 7th edition; Page no.280 – 285.
2.] Robbin’s Basic Pathology; 5th edition; Page no.608 – 610.