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DOXORUBICIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

February 9, 2020 GPAT Preparation, Study Material Acute myeloblastic leukemia, Bone sarcoma, Breast cancer, doxorubicin, doxorubicin gpat preparations, doxorubicin IUPAC, doxorubicin mechanism of action, doxorubicin method of synthesis, doxorubicin SAR, doxorubicin side effects, doxorubicin structure, doxorubicin therapeutic uses, Endometrial cancer, Gastric cancer, GPAT, gpat question papers, Head and neck cancer, Hodgkin’s lymphoma, Kidney cancer, Liver cancer, lung cancer, Multiple myeloma, Neuroblastoma, niper question papers, Non-Hodgkin’s lymphoma, Ovarian cancer, Remove term: Acute lymphoblastic leukemia Acute lymphoblastic leukemia Doxorubicin, Small cell, Soft, Thyomas, Thyroid cancer, tissue sarcoma, Transitional cell bladder cancer, Uterine sarcoma, Waldenstorm macroglobulinemia, Wilms’ tumor

Doxorubicin IUPAC nomenclature (7S,9S)-7-[(2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione. Classification Doxorubicin falls under the category of Anthracyclic antibiotic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 543.5 g/mol 2 Appearance Red crystalline solid 3 Melting point Range between […]

DAUNORUBICIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

January 31, 2020 GPAT Preparation, Study Material Acute lymphoblastic leukemia, Acute Myelogenous leukemia, Acute promyelocytic leukemia, daunorubicin, daunorubicin chemical uses, daunorubicin gpat, daunorubicin IUPAC, daunorubicin MOA, daunorubicin physical properties, daunorubicin SAR, daunorubicin side effects, daunorubicin structure, daunorubicin therapeutic effects, GPAT preparation, gpat question papers

Daunorubicin IUPAC nomenclature (8S,10S)-8-Acetyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione. Classification Duanorubicin falls under the category of Anthracyclic antibiotic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 527.5 g/mol 2 Appearance Thin red needle form 3 Melting point 208.5°C 4 […]

MITOXANTRON Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

January 31, 2020 GPAT Preparation, Study Material Acute Myelogenous leukemia, Advanced prostate cancer, Breast cancers, gpat question papers, mitoxantron therapeutic uses, mitoxantrone, mitoxantrone chemical properties, mitoxantrone chemical synthesis, mitoxantrone GPAT, mitoxantrone iupac, mitoxantrone MCQ, mitoxantrone mechanism of action, mitoxantrone physical properties, mitoxantrone SAR, mitoxantrone side effects, mitoxantrone structure, niper question papers, Non-Hodgkin’s lymphomas

Mitoxantron IUPAC nomenclature 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]-anthracene-9,10-dione. Classification Mitoxantron falls under the category of antibiotic Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 444.5g/mol 2 Appearance Present in liquid state. Can be obtained as blue-black solid […]

BLEOMYCINS Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

January 31, 2020 GPAT Preparation, Study Material bleomycin, bleomycin chemical properties, Bleomycin GPAT question, bleomycin iUPAC, bleomycin physical properties, bleomycin structure, bleomycine MCQ, bleomycine mechanism of action, bleomycine method of sythesis, bleomycine side effects, bleomycine therapeutic uses, e SAR, gpat question papers, Hodgkin’s lymphoma, Melanoma, niper question papers, Non-Hodgkin’s lymphoma, Ovarian cancer, Sarcoma, Squamous cell cancer, Testicular cancer

Bleomycins IUPAC nomenclature (3-{[(2′-{(5S,8S,9S,10R,13S)-15-{6-amino-2- [(1S)-3-amino-1-{[(2S)-2,3-diamino-3-oxopropyl]amino}-3-oxopropyl] -5-methylpyrimidin-4-yl}-13-[{[(2R,3S,4S,5S,6S)-3- {[(2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy} -4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy} (1H-imidazol-5-yl)methyl]-9-hydroxy-5-[(1R)-1-hydroxyethyl]-8,10-dimethyl-4,7,12,15-tetraoxo-3,6,11,14-tetraazapentadec-1-yl}-2,4′-bi-1,3-thiazol-4-yl)carbonyl]amino}propyl)(dimethyl)sulfonium. Classification Bleomycin falls under the category of antibiotic Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 1415.6 g/mol 2 Appearance Yellow to colorless […]

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DOXORUBICIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

DAUNORUBICIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

MITOXANTRON Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

BLEOMYCINS Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses