Tag: gpatindia

AZATHIOPRINE Synthesis, SAR, MCQ,Structure and Therapeutic Uses

Azathioprine  IUPAC nomenclature 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine     Classification Azathioprine falls under the category of purine antagonist antimetabolite. It is also an immunosuppressive agent. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 277.27 g/mol 2 Appearance Pale yellow crystalline […]

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METHOTREXATE SAR, Synthesis, Mechanism of action, Therapeutic actions, Side effects and MCQ

Methotrexate IUPAC nomenclature (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid   Classification Methotrexate falls under the category of Folate antagonist antimetabolite Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 454.4 g/mol 2 Appearance Yellow to brown crystalline powder 3 Melting point 195°C […]

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6-MERCAPTOPURINE SAR, synthesis, mechanism of action, therapeutic actions, side effects and mcq

6-Mercaptopurine (6-MP)  IUPAC nomenclature 3,7-dihydropurine-6-thione   Classification 6-Mercaptopurine falls under the category of purine antagonist antimetabolite. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 152.18g/mol 2 Appearance Yellow to dark yellow crystalline powder 3 Melting point 313 […]

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6-THIOGUANINE Synthesis, SAR, MCQ,Chemical Structure and Therapeutic Uses

6-Thioguanine (6-TG)    IUPAC nomenclature 2-amino-1H-purine-6(7H)-thione   Classification 6-Thioguanine falls under the category of purine antagonist antimetabolite. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 167.19g/mol 2 Appearance Yellow crystalline powder 3 Melting point More than 360 […]

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DACARBAZINE Synthesis, SAR, MCQ,Structure and Therapeutic Uses

Dacarbazine (DTIC) IUPAC nomenclature 5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide   Classification Dacarbazine falls under the category of Triazine alkalyting agents. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 182.18 g/mol 2 Appearance Ivory microcrystalline solid 3 Melting point 205°C 4 Solubility […]

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Carmustine (BCNU) Synthesis, SAR, MCQ,Chemical Structure and Therapeutic Uses

Carmustine (BCNU)  IUPAC nomenclature 1,3-Bis(2-chloroethyl)-1-nitrosourea   Classification Carmustine falls under the category of alkyl Nitrosoureas alkalyting agents. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 214.05 g/mol 2 Appearance Orange yellow solid 3 Melting point 31°C 4 […]

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BUSULFAN Synthesis, SAR, MCQ,Chemical Structure and Therapeutic Uses

Busulfan  IUPAC nomenclature Butane-1,4-diyl dimethanesulfonate Classification Busulfan falls under the category of alkyl sulfonate alkalyting agents. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 246.3 g/mol 2 Appearance White crystalline solid 3 Melting point 114-118°C 4 Solubility […]

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THIOTEPA Synthesis, SAR, MCQ and Chemical Structure

Thiotepa  IUPAC nomenclature 1,1′,1′′-Phosphorothioyltriaziridine Classification Thiotepa falls under the category of ethylenimine alkalyting agents. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 189.22 g/mol 2 Appearance White crystalline solid 3 Melting point 51.5°C 4 Solubility 19 mg […]

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MELPHALAN Synthesis, SAR, MCQ and Chemical Structure

Melphalan It is a Anticancer Drug.  IUPAC nomenclature 4-[bis(2-Chloroethyl)amino]-L-phenylalanine Classification Melphalan falls under the category of Nitrogen mustard alkalyting agents. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 305.2 g/mol 2 Appearance White to buff colored powder 3 […]

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