Flow Property: (1) The flow properties of solids have great impact on the tableting processes since their manufacturing require the flow of powder from a storage container to tablet dies. (2) Weight and content uniformity are also dependent on flow […]
Micromeritics is the science and technology of small particles and includes the study of the fundamental and derived properties of individual as well as a collection of particles. The micromeritic properties of a drug can be related in a significant […]
Average particle size: Suppose that the particle size of a powder is analysed and the number of particles in each size range is determined, from the data, the average particle size of the powder may be calculated as Davg = […]
Optical Microscopy: Equivalent diameter: It is used to determine projected area diameter, Feret’s diameter and Martin’s diameter. Range of analysis: 1 μm to about 100 μm. Methodology: Firstly, the powdered substance is placed over the stage and obseved through the […]
Specific surface: The specific surface of a powder is defined as the surface area per unit volume (Sv) or per unit weight (Sw). SURFACE AREA DETERMINATION METHODS: The surface area can be determined directly by one of the following two […]
Density (Ƿ): Density is defined as weight per unit volume. Based on the types of volume defined, the corresponding ‘density’ may be proposed. Table 1 – Types of densities Density Dełnition Formula Determination Comment Bulk(Ƿb) Mass divided by bulk volume […]