Anti Cancer Drug Mechanism-Tyrosine kinase Inhibitors, Side effects & Uses || GPAT || NEET PG

Anti Cancer Drug Mechanism- Tyrosine kinase Inhibitors In this lecture Mechanism of action of Tyrosine Kinase Inhibitor discussed.

As well As Pharmacology of Various drugs from this category like

  • Imatinib,
  • Dasatinib,
  • Nilotinib

Side effects Mnemonics Discussed for Imatinib.

These Targeted anticancer drugs are used for Chronic Myleoid Leukemia (CML), Gatrointestinal Stromal Tumor (GIST), Dermatofiber Sarcoma.


MCQ on Anticancer Tyrosine Kinase Inhibitors

Q. 1 Which of the Following Drug bind with Tyrosine Kinase Receptor

A. Imatinib

B. Dasatinib

C. Nilotinib

D. All of these

Q. 2 In Which stage Imatinib bind with Tyrosine Kinase Receptor

A. Inactive Stage of Receptor

B. Active Stage of Receptor

C. Both

D. None

Q. 3 Dasatinib bind with Tyrosine Kinase Receptor

A. Inactive Stage

B. Active Stage

C. Both

D. None

Q. 4 Side Effect of Imatinib is/are

A. Periorbital Edema

B. Pleural Edema

C. Fluid Retention

D. All of these

Q. 5 Which of the following Drug is used in Imatinib Resistant Philadelphia Chromosome Positive Cases of CML

A. Dasatinib

B. Vincristine

C. Both

D. None

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