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DUTASTERIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Dutasteride IUPAC nomenclature (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide. Classification Dutasteride is a 5-α reductase inhibitor. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 528.5 g/mol 2 Appearance Solid 3 Melting point 242-250°C 4 Solubility Insoluble 5 Octanol/water partition coefficient 6.8 […]

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NAFARELIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Nafarelin IUPAC nomenclature (2R)-N-[(2R)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[(2R)-2-[(2R)-2-[(2R)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2R)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-(naphthalen-2-yl)propanamido]-4-methylpentanamide.   Classification Nafarelin is a GnRH analogue. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 1322.5 g/mol 2 Appearance White to off white solid 3 Melting point More than 181°C 4 Solubility […]

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Squill: Biological sources,Morphological features, MCQs and Medicinal Uses

SQUILL 1. Biological sources: • The botanical name of squill is Drimia maritima. • The biological source of squill is dried slices of bulb urginea indica kunth. • It is also known as urginea, scillae bulbus, scilla bulb, white squill […]

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BICALUTAMIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Bicalutamide IUPAC nomenclature (RS)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide.   Classification Bicalutamide is an antiandrogen. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 430.4 g/mol 2 Appearance Fine white to off white powder 3 Melting point 191-193°C 4 Solubility Soluble in […]

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FLUTAMIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Flutamide IUPAC nomenclature 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide.   Classification Flutamide is an antiandrogen. [1]   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 276.21 g/mol 2 Appearance Solid 3 Melting point 111.5°C 4 Solubility 9.45 mg/L 5 Octanol/water partition coefficient […]

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Duboisea: Biological Source, Medicinal Uses, Morphological Features and MCQs

DUBOISEA 1. Biological source: • The botanical name of duboisea is Duboisia myoporoides. • The biological source of duboisea is its dried leaves. • It belongs to the solanaceae family. • It is also known as corkwood and cork tree. […]

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