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HOMATROPIN (HYOSCINE) Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Homatropin IUPAC nomenclature (N-Methyl-8-azabicyclo[3.2.1]oct-3-yl) 2-hydroxy-2-phenylacetate.   Classification Homatropin is a acetylcholine antagonist-muscarinic antagonist. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 275.34 g/mol 2 Physical appearance White to fine-white crystalline powder 3 Melting point 99.5°C. 4 Solubility […]

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TIOTROPIUM Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Tiotropium IUPAC nomenclature 7-[(hydroxidi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide   Classification Tiotropium is a long-acting, antimuscarinic bronchodilator. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 392.5 g/mol 2 Physical appearance Solid 3 Melting point 218-220°C. 4 Solubility Feely soluble in dimethyl […]

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TROSPIUM CHLORIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Trospium chloride IUPAC nomenclature 3‑(2‑Hydroxy-2,2‑diphenylacetoxy)spiro[bicyclo[3.2.1]octane-8,1’‑pyrrolidin]-1’‑ium chloride.   Classification Trospium is an antispasmodic agent. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 428 g/mol 2 Physical appearance Colorless to slightly yellow, fine crystalline solid. 3 Melting point 255-258°C. […]

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