Category: GPAT Preparation

NOREPINEPHRINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Norepinephrine IUPAC nomenclature (R)-4-(2-amino-1-hydroxyethyl)benzene-1,2-diol. Classification Norepinephrine is a nonselective adrenergic agonist. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 169.18g/mol 2 Physical appearance Present in colorless microcrystal form 3 Melting point 217°C 4 Solubility Very soluble […]

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TRIPTORELIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Triptorelin IUPAC nomenclature 5-oxo-D-prolyl-L-histidyl-Ltryptophyl-L-seryl-Ltyrosyl-3-(1H-indol-2-yl)-L-alanylleucyl-L-arginyl-L-prolylglycinamide.   Classification Triptorelin is a GnRH analogue. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 1311.4 g/mol 2 Physical appearance White to off white powder. Present in salt form as triptorelin pamoate […]

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FINASTERIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Finasteride IUPAC nomenclature (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide.   Classification Finasteride is a 5-α reductase inhibitor. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 372.5g/mol 2 Appearance Fine white to off white crystalline solid 3 Melting point 252-254°C 4 Solubility […]

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DUTASTERIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Dutasteride IUPAC nomenclature (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide. Classification Dutasteride is a 5-α reductase inhibitor. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 528.5 g/mol 2 Appearance Solid 3 Melting point 242-250°C 4 Solubility Insoluble 5 Octanol/water partition coefficient 6.8 […]

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NAFARELIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Nafarelin IUPAC nomenclature (2R)-N-[(2R)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[(2R)-2-[(2R)-2-[(2R)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2R)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-(naphthalen-2-yl)propanamido]-4-methylpentanamide.   Classification Nafarelin is a GnRH analogue. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 1322.5 g/mol 2 Appearance White to off white solid 3 Melting point More than 181°C 4 Solubility […]

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Squill: Biological sources,Morphological features, MCQs and Medicinal Uses

SQUILL 1. Biological sources: • The botanical name of squill is Drimia maritima. • The biological source of squill is dried slices of bulb urginea indica kunth. • It is also known as urginea, scillae bulbus, scilla bulb, white squill […]

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