Midazolam IUPAC nomenclature 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine Classification Midazolam is a benzodiazepine sedative-hypnotic. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 325.8 g/mol 2 Physical appearance White to light yellow crystalline solid 3 Melting point 159°C 4 Octanol/water partition coefficient […]
Eszopiclone IUPAC nomenclature (S)-(+)-6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl-4-methyl-1-piperazinecarboxylate Classification Eszopiclone is a nonbenzodiazepine sedative-hypnotic. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 388.8 g/mol 2 Physical appearance White to light yellow crystalline solid 3 Melting point 202-203°C 4 Octanol/water partition […]
Zaleplon IUPAC nomenclature N-(3-(3-cyanopyrazolo[1,5-a] pyrimidin-7-yl)phenyl)-N-ethylacetamide Classification Zaleplon is a nonbenzodiazepine sedative-hypnotic. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 305.33 g/mol 2 Physical appearance Solid 3 Melting point 157-159°C 4 Octanol/water partition coefficient 0.9 5 Solubility Very […]
¹³C NMR Although ¹²C is not observed in NMR,only ¹³C is observed in NMR. ¹³C is 1.1% present in nature. The relatively low abundance of ¹³C is over come by using single avaraging and Fourier transforms. ¹³C (267.53) has lower gyromateric ratio as compared […]
NMR PRINCIPAL :- Nuclei with odd mass or odd number have only property of nuclear spin. Spin quantum number is more than 0 so compound are NMR active. Spin quantum number is denoted by “I” If the external magnetic field is […]
Hydroxyamphetamine IUPAC nomenclature 4-(2-aminopropyl)phenol Classification Hydroxyamphetamine is an indirect acting sympathomimetic amine drug having adrenergic properties. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 151.21 g/mol 2 Physical appearance White to off-white crystalline powder 3 Melting […]
SOLVENT USED IN NMR Solvent that are used in NMR should not contain Hydrogen atom. It is magnetically isotropic in nature means all directions they are equally magnetic field. Solvent are also following characteristics chemically inactive, volatile in nature, solvent able […]
Methacholine IUPAC nomenclature 2-(Acetyloxy)-N,N,N-trimethylpropan-1-aminium. Classification Methacholine is a cholinergic agonist falls in the class of choline esters. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 160.23 g/mol 2 Physical appearance Present in solid form 3 Melting […]
Pilocarpine IUPAC nomenclature (3S,4R)-3-Ethyl-4-((1-methyl-1H-imidazol-5-yl)methyl)dihydrofuran-2(3H)-one. Classification Pilocarpine is a cholinergic agonist falls in the class of alkaloids. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 208.26 g/mol 2 Physical appearance Present in oil or crystal (needle) form. […]
Labetolol IUPAC nomenclature (RS)-2-Hydroxy-5-[1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl]benzamide. Classification Labetolol is a mixed α/ß blocker. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 328.4 g/mol 2 Physical appearance Solid 3 Melting point 188°C 4 Solubility Water solubility is 3.56e-04 […]