Overview Definition: Glycogen Storage Diseases are a group of inherited metabolic disorders caused by deficiencies in enzymes involved in glycogen synthesis, degradation, or regulation. Inheritance: Mostly autosomal recessive, except for GSD IX (X-linked in some cases). General Symptoms: Hypoglycemia, hepatomegaly, […]
SOLUBILIZATION: It can be defined as the preparation of a thermodynamically stable isotropic solution of a substance normally insoluble or very slightly soluble in a given solvent by the addition of component or by any suitable methods. SOLUBILITY: The maximum […]
In pyrimidine synthesis, firstly the pyrimidine ring is formed and then ribose phosphate group is attached. This ribose phosphate group is donated by PRPP (phosphoribosyl-pyrophosphate). The major pyrimidine nucleotide involve: TMP, CMP and UMP. Precursors for the De-novo synthesis of […]
Catabolism of purine nucleotide The end product of catabolism of purine is uric acid. Mammals oxidize the uric acid to allantoin, which further get converted into urea and then ammonia. Reactions of catabolism of purine nucleotide Firstly the phosphate group […]