” SCID (Severe combined immunodeficiency) is basically caused due to the deficiency of an enzyme called adenosine deaminase enzyme. In this group of immunodeficiency disease, there is a B – cell and T – cell defect which are its characteristic […]
” The thalassemia is a heterogeneous group of mendalian disorder, all characterized by lack of or decreased synthesis of either the alpha or the beta globin chain of hemoglobin A (α2β2).” 1.] Thalassemia, unlike haemoglobinopathies which are the qualitative disorders […]
The electron transport chain (ETC) also known as respiratory chain is the final pathway in aerobic cells by which the electrons are transferred to the oxygen. These electrons are derived from various substrates. ETC contains a series of oxidation, reduction […]
Most of the NADH and FADH2 which enters the mitochondrial ETC, arises from the kreb’s cycle or beta-oxidation of fatty acids. Now since the inner mitochondrial membrane is impermeable to the cytoplasmic NADH, so that’ why the NADH generated through […]
Nucleic acids are the macromolecules in the living cells. When these nucleic acids combine with proteins, they form nucleoproteins. The protein components are protamine and histones. Nucleic acids are polymers of nucleotides which are linked by phosphor-di-ester bond and are […]
Purine and pyrimidine are dietary non-essential components. Dietary nucleic acid and nucleotides do not provide essential components for the synthesis of endogenous nucleic acids. In humans, the synthesis of nucleic acid is done by de-novo routes, that its through amphibolic […]