Category: Medicinal Chemistry

METHYCLOTHIAZIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Methyclothiazide   IUPAC nomenclature 6-Chloro-3-(chloromethyl)-2-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide   Classification Thiazide diuretic   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 360.2 g/mol 2 Physical appearance White crystalline powder 3 Melting point 225oC 4 Solubility Slightly soluble in alcohol; […]

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ANTI-INFLAMMATORY AGENTS Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

ANTI-INFLAMMATORY AGENTS acetaminophen Click here phenacetin Click here zomepriac Click here etodolac Click here nabumetone Click here ibuprofen Click here fenoprofen Click here ketoprofen Click here naproxen Click here flubiprofen Click here ketorolac Click here mefenamic acid Click here flufenamic […]

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PHENIRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Pheniramine   IUPAC nomenclature N,N-Dimethyl-3-phenyl-3-pyridin-2-yl-propan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 240.34g/mol 2 Physical appearance Solid 3 Melting point <25oC 4 Solubility 3.77e-01 g/L 5 Presence of ring Pyridine,  […]

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PYRROBUTAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Pyrrobutamine IUPAC nomenclature 1-[(2E)-4-(4-chlorophenyl)-3-phenylbut-2-en-1-yl]pyrrolidine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 311.8 g/mol 2 Physical appearance N/A 3 Melting point N/A 4 Solubility N/A 5 Presence of ring Pyrrolidine,  phenyl […]

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CHLORPHENIRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Chlorpheniramine IUPAC nomenclature 3-(4-Chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 274.79 g/mol 2 Physical appearance White crystalline solid 3 Melting point 130-135oC 4 Solubility 160 mg/ml 5 Octanol/water partition […]

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BROMPHENIRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Brompheniramine IUPAC nomenclature (R/S)-3-(4-Bromophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 319.24 g/mol 2 Physical appearance Yellow oily liquid 3 Melting point <25oC 4 Solubility Soluble in dilute acids 5 […]

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