Tag: gpatindia

NUTRITIONAL REQUIREMENT FOR BACTERIAL GROWTH AND FACTORS AFFECTING BACTERIAL GROWTH

NUTRITIONAL REQUIREMENT FOR BACTERIAL GROWTH AND FACTORS AFFECTING BACTERIAL GROWTH Nutritional requirements for the bacterial growth Water covers 70% of the total bacterial mass. Two important gaseous constituents in microorganism are oxygen and hydrogen. Other than these, carbon, nitrogen , […]

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PHENIRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Pheniramine   IUPAC nomenclature N,N-Dimethyl-3-phenyl-3-pyridin-2-yl-propan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 240.34g/mol 2 Physical appearance Solid 3 Melting point <25oC 4 Solubility 3.77e-01 g/L 5 Presence of ring Pyridine,  […]

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PYRROBUTAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Pyrrobutamine IUPAC nomenclature 1-[(2E)-4-(4-chlorophenyl)-3-phenylbut-2-en-1-yl]pyrrolidine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 311.8 g/mol 2 Physical appearance N/A 3 Melting point N/A 4 Solubility N/A 5 Presence of ring Pyrrolidine,  phenyl […]

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CHLORPHENIRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Chlorpheniramine IUPAC nomenclature 3-(4-Chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 274.79 g/mol 2 Physical appearance White crystalline solid 3 Melting point 130-135oC 4 Solubility 160 mg/ml 5 Octanol/water partition […]

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BROMPHENIRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Brompheniramine IUPAC nomenclature (R/S)-3-(4-Bromophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 319.24 g/mol 2 Physical appearance Yellow oily liquid 3 Melting point <25oC 4 Solubility Soluble in dilute acids 5 […]

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TRIPROLIDINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Triprolidine IUPAC nomenclature 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl-prop-1-enyl]pyridine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 278.4 g/mol 2 Physical appearance Forms crystal from light petroleum 3 Melting point 60oC 4 Solubility 74.9 mg/LL 5 […]

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DIMETHINDENE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Dimethindene IUPAC nomenclature N,N-Dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 292.4 g/mol 2 Physical appearance Solid 3 Melting point 158oC 4 Solubility 239 mg/LL 5 Octanol/water partition coefficient N/A […]

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DIMENHYDRINATE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Dimenhydrinate Chemical composition Diphenhydramine (53-55.5%) + 8-Chlorotheophylline (44-47%) IUPAC nomenclature 2-benzhydryloxy-N,N-dimethylethanamine;8-chloro-1,3-dimethyl-7H-purine-2,6-dione   Classification H1-receptor antihistamine Ethanolamine ether antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 470 g/mol 2 Physical appearance Crystalline white powder 3 Melting […]

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