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FLUTAMIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Flutamide IUPAC nomenclature 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide.   Classification Flutamide is an antiandrogen. [1]   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 276.21 g/mol 2 Appearance Solid 3 Melting point 111.5°C 4 Solubility 9.45 mg/L 5 Octanol/water partition coefficient […]

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Duboisea: Biological Source, Medicinal Uses, Morphological Features and MCQs

DUBOISEA 1. Biological source: • The botanical name of duboisea is Duboisia myoporoides. • The biological source of duboisea is its dried leaves. • It belongs to the solanaceae family. • It is also known as corkwood and cork tree. […]

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ANASTROZOLE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Anastrozole IUPAC nomenclature 2,2′-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile). Classification Anastrozole is an aromatase inhibitor. [1]   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 293.4 g/mol 2 Appearance Off white powder form 3 Melting point 82°C 4 Solubility 0.53mg/ml in water […]

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LETROZOLE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Letrozole IUPAC nomenclature 4,4′-((1H-1,2,4-triazol-1-yl)methylene)dibenzonitrile. Classification Letrozole is an aromatase inhibitor. [1]   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 285.3 g/mol 2 Appearance White to yellow crystalline powder. It is present in anhydrous crystal form 3 […]

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FULVESTRANT Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Fulvestrant IUPAC nomenclature (7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol. Classification Fulvestrant  is a selective estrogen receptor down regulator. [1]   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 606.8 g/mol 2 Appearance Present as white powder form. The solution for injection appears […]

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TOREMIFENE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Toremifene IUPAC nomenclature 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-but-1-en-1-yl]phenoxy]-N,N-dimethylethanamine.   Classification Toremifene is a selective estrogen receptor modulator. [1]   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 406 g/mol 2 Appearance Present in the solid form 3 Melting point 108-110°C 4 […]

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TAMOXIFEN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Tamoxifen IUPAC nomenclature (Z)-2-[4-(1,2-Diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine. Classification Tamoxifen is a selective estrogen receptor modulator. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 371.5  g/mol 2 Appearance Present in solid form 3 Melting point 97°C 4 Solubility 16.7  mg […]

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