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CHLORCYCLIZINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Chlorcyclizine IUPAC nomenclature 1-[(4-Chlorophenyl)(phenyl)methyl]-4-methylpiperazine Classification H1-receptor antihistamine Piperazine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 300.8g/mol 2 Physical appearance Oil 3 Melting point 216oC 4 Solubility Water solubility is 0.0424 mg/ml 5 Octanol/water partition […]

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HYDROXYZINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Hydroxyzine IUPAC nomenclature (±)-2-(2-{4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl}ethoxy)ethanol Classification H1-receptor antihistamine Piperazine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 374.9 g/mol 2 Physical appearance Solid or oil 3 Melting point 190oC 4 Solubility 428 mg/L in water 5 […]

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PROMETHAZINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Promethazine IUPAC nomenclature N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine Classification H1-receptor antihistamine Phenothiazine derivative antihistamine drug   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 284.4 g/mol 2 Physical appearance White to faint yellow crystalline powder 3 Melting point 60oC 4 Solubility […]

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TRIMEPRAZINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Trimeprazine Or Alimemazine   IUPAC nomenclature 10-(3-dimethylamino-2-methylpropylphenothiazine Classification H1-receptor antihistamine Phenothiazine derivative antihistamine drug   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 298.4 g/mol 2 Physical appearance Crystals 3 Melting point 68oC 4 Solubility 0.942 mg/ml […]

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CYPROHEPTIDINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Cyproheptadine IUPAC nomenclature 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine Classification H1-receptor antihistamine Piperidine derivative antihistamine drug   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 287.4 g/mol 2 Physical appearance Crystals from dilute ethanol 3 Melting point 112.8oC 4 Solubility Soluble 5 […]

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