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ESOMEPRAZOLE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Esomeprazole   IUPAC nomenclature (S)-(−)-5-Methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-3H-benzoimidazole Classification Proton pump inhibitors   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 345.4  g/mol 2 Physical appearance Solid 3 Melting point 155 oC 4 Solubility Very soluble in water 5 Octanol/water […]

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LANSOPRAZOLE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Lansoprazole IUPAC nomenclature 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole Classification Proton pump inhibitors Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 369.4  g/mol 2 Physical appearance White to brownish-white crystalline powder 3 Melting point 178-182oC 4 Solubility Freely soluble in dimethylformamide; insoluble […]

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DEXLANSOPRAZOLE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Dexlansoprazole IUPAC nomenclature (R)-(+)-2-([3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl)-1H-benzo[d]imidazole Classification Proton pump inhibitors   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 369.4  g/mol 2 Physical appearance White to brownish-white crystalline powder 3 Melting point 140oC 4 Solubility 0.21 mg/ml 5 Octanol/water […]

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RABEPRAZOLE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Rabeprazole IUPAC nomenclature (RS)-2-([4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl)-1H-benzo[d]imidazole. Classification Proton pump inhibitors   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 359.4  g/mol 2 Physical appearance White to yellowish white solid 3 Melting point 99-100oC 4 Solubility Very soluble in water […]

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PANTOPRAZOLE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Pantoprazole   IUPAC nomenclature (RS)-6-(Difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzo[d]imidazole Classification Proton pump inhibitors   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 383.4 g/mol 2 Physical appearance Off-white solid 3 Melting point 139-140oC 4 Solubility Freely soluble in water 5 Octanol/water […]

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NITROGLYCERINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Nitroglycerine Or Glyceryl trinitrate   IUPAC nomenclature 1,3-dinitrooxypropan-2-yl nitrate; [3-(nitrooxy)-2-[(nitrooxy)methyl]propyl] nitrate; 1,2,3-trinitroxypropane. Classification Organic nitrate antianginal drug   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 227.09 g/mol 2 Physical appearance Colorless solution 3 Melting point 13.5oC […]

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