Category: GPAT Preparation

PROCARBAZINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Procarbazine IUPAC nomenclature N-Isopropyl-4-[(2-methylhydrazino)methyl]benzamide   Classification Procarbazine  falls under the category of Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 221.3 g/mol 2 Appearance Present in solid form 3 Melting point 223°C 4 […]

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HYDROXYUREA Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Hydroxyurea IUPAC nomenclature Hydroxyurea   Classification Hydroxurea  falls under the category of Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 76.055 g/mol 2 Appearance White to off-white crystalline solid 3 Melting point 141°C […]

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ACTINOMYCIN D Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Actinomycin D (Dactinomycin) IUPAC nomenclature 2-Amino-N,N′- bis[(6S,9R,10S,13R,18aS)-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide. Classification Actinomycin D falls under the category of Antibiotic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 1255.4g/mol 2 Appearance Bright red rhomboid prisms / red powder […]

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DAUNORUBICIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Daunorubicin IUPAC nomenclature (8S,10S)-8-Acetyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione. Classification Duanorubicin falls under the category of Anthracyclic antibiotic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 527.5 g/mol 2 Appearance Thin red needle form 3 Melting point 208.5°C 4 […]

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MITOXANTRON Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Mitoxantron IUPAC nomenclature 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]-anthracene-9,10-dione. Classification Mitoxantron falls under the category of antibiotic Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 444.5g/mol 2 Appearance Present in liquid state. Can be obtained as blue-black solid […]

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BLEOMYCINS Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Bleomycins IUPAC nomenclature (3-{[(2′-{(5S,8S,9S,10R,13S)-15-{6-amino-2- [(1S)-3-amino-1-{[(2S)-2,3-diamino-3-oxopropyl]amino}-3-oxopropyl] -5-methylpyrimidin-4-yl}-13-[{[(2R,3S,4S,5S,6S)-3- {[(2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy} -4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy} (1H-imidazol-5-yl)methyl]-9-hydroxy-5-[(1R)-1-hydroxyethyl]-8,10-dimethyl-4,7,12,15-tetraoxo-3,6,11,14-tetraazapentadec-1-yl}-2,4′-bi-1,3-thiazol-4-yl)carbonyl]amino}propyl)(dimethyl)sulfonium. Classification Bleomycin falls under the category of antibiotic Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 1415.6 g/mol 2 Appearance Yellow to colorless […]

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