A suppository is a solid dosage form in which one or more APIs are dispersed in a suitable base and molded or otherwise formed into a suitable shape for insertion into the rectum to provide local or systemic effect. Suppositories […]
Dissolution Test Parameters: Eccentricity of the stirring device – The United States Pharmacopeia (USP) specifies that the stirring shaft must rotate smoothly without significant wobble. Eccentricity can be measured in terms of total indicator reading(TIR) with the help of machinist’s […]
ANTIMICROBIAL DRUGS- GENERAL CONSIDERATIONS Antimicrobial drugs: Antimicrobial drugs are chemical substances of natural or synthetic origin that suppress the growth of, or destroy, micro-organisms including bacteria, fungi, helminths, protozoa and viruses. Antimicrobial drugs include: antibiotics, chemotherapeutic agents. Classifications: These drugs […]
Antiemetics: Antiemetics are a heterogeneous group of drugs used to treat various causes of nausea and vomiting. Different antiemetics act on different receptors, and they may have a peripheral effect, a central effect, or both. Antiemetic drugs can help when nausea […]
Emesis: Vomiting is rarely painful, but never pleasant. Vomiting, also known scientifically as “emesis” and colloquially as throwing up, retching, heaving, or being sick, is the forcible voluntary or involuntary emptying of stomach contents through the mouth or, less often, […]
Diarrhoea: Diarrhoea is when your bowel movements become loose or watery. The definition of diarrhoea is passing loose or watery bowel movements 3 or more times in a day. Diarrhoea occurs when the lining of the intestine is unable to […]
Constipation: It is a condition where there is infrequent bowel movement. Causes: Diet( lack of fibers and liquids), lack of exercise, age, […]
Ointment bases are generally classified by the USP into four groups I. Oleaginous bases II. Absorption bases III. Water removable bases IV. Water soluble bases 1)Oleaginous bases – Oleaginous bases are also termed as hydrocarbon bases. On application to the […]