Solubility of Liquid in Liquid: Frequently two or more liquids are mixed together in the preparation of pharmaceutical products (e.g. aromatic waters, spirits, elixirs, lotions, sprays, and medicated oils). Liquid–liquid systems can be divided into two categories according to the […]
Solubility of solids in liquids: Factors influencing solubility- Particle size (surface area) of drug particles ↓Particle size → ↑ surface area→ ↑Solubility. Log S/So = 2ϒv/2.303RTr So is the solubility of large particles S is the solubility of fine particles […]
Ideal and Real Solutions: Ideal solution: No change in the properties of the components, other than dilution, when they are mixed to form the solution. No heat is evolved or absorbed during the mixing process, The final volume of the […]
SOLVATION: The interaction between solute and solvent molecule which leads to stabilisation of solute species in the solution is called as solvation. The strength and nature of interaction between the solute molecule and solvent influences many properties of solute like […]
Matter: The definition of Matter is anything that has mass and volume (takes up space). States of matter: Matter exists in one of the three states-solid liquid or gas. Two factors usually determined the state in which matter exist. One is the intensity of […]
Gases are compressible fluid and has no definite shape. Properties of Gases: 1) A sample of gas assumes both the shape and volume of the container. 2) Gases are compressible. 3) The densities of gases are much smaller than those […]
Relative humidity: It is a ratio, expressed in percent, the amount of atmospheric moisture present relative to the amount that would be present if the air is saturated. Since the later amount is dependent on temperature. Relative humidity is a […]
SETTLING IN SUSPENSIONS : One aspect of physical stability in pharmaceutical suspensions is concerned with keeping the particles uniformly distributed throughout the dispersion. It possible to prevent settling completely over a prolonged period of time, it is necessary to consider the […]