Category: NEET PG

NUTRITIONAL REQUIREMENT FOR BACTERIAL GROWTH AND FACTORS AFFECTING BACTERIAL GROWTH

NUTRITIONAL REQUIREMENT FOR BACTERIAL GROWTH AND FACTORS AFFECTING BACTERIAL GROWTH Nutritional requirements for the bacterial growth Water covers 70% of the total bacterial mass. Two important gaseous constituents in microorganism are oxygen and hydrogen. Other than these, carbon, nitrogen , […]

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PHENIRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Pheniramine   IUPAC nomenclature N,N-Dimethyl-3-phenyl-3-pyridin-2-yl-propan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 240.34g/mol 2 Physical appearance Solid 3 Melting point <25oC 4 Solubility 3.77e-01 g/L 5 Presence of ring Pyridine,  […]

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PYRROBUTAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Pyrrobutamine IUPAC nomenclature 1-[(2E)-4-(4-chlorophenyl)-3-phenylbut-2-en-1-yl]pyrrolidine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 311.8 g/mol 2 Physical appearance N/A 3 Melting point N/A 4 Solubility N/A 5 Presence of ring Pyrrolidine,  phenyl […]

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CHLORPHENIRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Chlorpheniramine IUPAC nomenclature 3-(4-Chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 274.79 g/mol 2 Physical appearance White crystalline solid 3 Melting point 130-135oC 4 Solubility 160 mg/ml 5 Octanol/water partition […]

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BROMPHENIRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Brompheniramine IUPAC nomenclature (R/S)-3-(4-Bromophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 319.24 g/mol 2 Physical appearance Yellow oily liquid 3 Melting point <25oC 4 Solubility Soluble in dilute acids 5 […]

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TRIPROLIDINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Triprolidine IUPAC nomenclature 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl-prop-1-enyl]pyridine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 278.4 g/mol 2 Physical appearance Forms crystal from light petroleum 3 Melting point 60oC 4 Solubility 74.9 mg/LL 5 […]

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DIMETHINDENE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Dimethindene IUPAC nomenclature N,N-Dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 292.4 g/mol 2 Physical appearance Solid 3 Melting point 158oC 4 Solubility 239 mg/LL 5 Octanol/water partition coefficient N/A […]

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DOXYLAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Doxylamine IUPAC nomenclature (RS)-N,N-dimethyl-2-(1-phenyl-1-pyridin-2-yl-ethoxy)-ethanamine Classification H1-receptor antihistamine Ethanolamine ether antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 270.37 g/mol 2 Physical appearance Clear colorless liquid 3 Melting point <25oC 4 Solubility Soluble in acids 5 […]

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CLEMASTINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Clemastine IUPAC nomenclature  (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine Classification H1-receptor antihistamine Ethanolamine ether antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 343.9 g/mol 2 Physical appearance Solid 3 Melting point 178oC 4 Solubility Hydrogen fumarate formulation is soluble 5 […]

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