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PREDNISOLONE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

February 21, 2020February 21, 2020 GPAT Preparation, MCQ, Pharmacy Exam Questions, Study Material chiral centers in prednisolone, gpatindia, monoclinic space in prednisolone, orthorhombic form in prednisolone, PREDNISOLONE, Prednisolone Allergic reactions, Prednisolone Asthma, Prednisolone Autoimmune diseases, PREDNISOLONE chemical properties, Prednisolone decreases vasodilation, PREDNISOLONE gpat questions, PREDNISOLONE gpatindia, Prednisolone Inflammations in various parts of body, Prednisolone Leukemia, Prednisolone Lymphoma, PREDNISOLONE mechanism of action, Prednisolone Multiple myeloma, Prednisolone Nausea, PREDNISOLONE physical properties, PREDNISOLONE SAR, PREDNISOLONE side effects, Prednisolone Skin diseases, PREDNISOLONE structure, PREDNISOLONE synthesis, PREDNISOLONE therapeutic uses, Prednisolone Vomiting, two polymorphic forms of Prednisolone

Prednisolone IUPAC nomenclature (11β)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione. Classification Prednisolone falls under the category of glucocorticoids. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 360.4 g/mol 2 Appearance White crystalline powder. Prednislolone have one sesquihydrate and two polymorphic forms […]

CISPLATIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

February 14, 2020February 21, 2020 GPAT Preparation, MCQ, Pharmacy Exam Questions, Study Material Advanced bladder cancer, Bladder cancer, Breast cancer, Cerviacal cancer, CISPLATIN, CISPLATIN chemical properties, CISPLATIN gpat questions, CISPLATIN gpatindia, CISPLATIN mechanism of action, CISPLATIN physical properties, CISPLATIN SAR, CISPLATIN side effects, CISPLATIN structure, CISPLATIN synthesis, CISPLATIN therapeutic uses, Esophageal cancer, gpatindia, Head and neck cancer, Hodgkin’s lymphomas, Melanoma, Mesothelioma, Metastatic cancer, Metastatic ovarian cancer, Multiple myeloma, Neuroblastoma, Non-Hodgkin’s lymphoma, Non-small cell lung cancer, Ovarian cancer, Prostate cancer, Sarcomas, Small cell lung cancer, Stomach cancer, Testicular cancer

Cisplatin IUPAC nomenclature (SP-4-2)-diamminedichloroplatinum(II) Classification Cisplatin falls under the category of Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 300 g/mol 2 Appearance Platinol vials contains cisplatin as a lyophilized powder form. 3 […]

CARBOPLATIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

February 14, 2020 GPAT Preparation, MCQ, Pharmacy Exam Questions, Study Material Bladder cancer, Breast cancer, CARBOPLATIN, CARBOPLATIN chemical properties, CARBOPLATIN gpat questions, CARBOPLATIN gpatindia, CARBOPLATIN mechanism of action, CARBOPLATIN physical properties, CARBOPLATIN SAR, CARBOPLATIN side effects, CARBOPLATIN structure, CARBOPLATIN synthesis, CARBOPLATIN therapeutic uses, Cervical cancer, CNS tumors, Endometrial cancer, Esophageal cancer, Germ cell tumors, gpatindia, Head and neck cancer, lung cancer, Medicinal Chemistry MCQ anticancer drugs, Osteogenic sarcoma, Ovarian cancer

Carboplatin IUPAC nomenclature Cis diammine(cyclobutane-1,1-dicarboxylate-O,O’)platinum(II) Classification Carboplatin falls under the category of Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 371.25g/mol 2 Appearance White crystals 3 Melting point 228-230°C 4 Solubility Soluble in […]

IMATINIB Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

February 14, 2020 GPAT Preparation, MCQ, Pharmacy Exam Questions, Study Material Gastrointestinal stromal tumors which are C-kit positive, gpatindia, IMATINIB, IMATINIB chemical properties, Imatinib consists of a methylbenzene ring, Imatinib consists of a pyrimidine ring, Imatinib consists of aminopyrimidine ring, IMATINIB gpat questions, IMATINIB gpatindia, IMATINIB mechanism of action, IMATINIB physical properties, IMATINIB SAR, IMATINIB side effects, IMATINIB structure, IMATINIB synthesis, IMATINIB therapeutic uses, Myelodysplastic/ myeloproliferative diseases associated with PDGFR gene rearrangements, Philadelphia chromosome positive acute lymphoblastic leukemia, Philadelphia chromosome positive chronic myeloid leukemia

Imatinib IUPAC nomenclature 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide. Classification Imatinib falls under the category of antibiotic Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 493.6 g/mol 2 Appearance Present in solid form 3 Melting point 226°C 4 […]

PROCARBAZINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

February 9, 2020 GPAT Preparation, Study Material Brain tumors, gpatindia, Hodgkin’s disease, lung cancer, Melanoma, Multiple myeloma, Non-Hodgkin’s lymphoma, Pharmacist question on cancer drugs, PROCARBAZINE, PROCARBAZINE chemical properties, PROCARBAZINE gpat questions, PROCARBAZINE gpatindia, PROCARBAZINE mechanism of action, PROCARBAZINE physical properties, PROCARBAZINE SAR, PROCARBAZINE side effects, PROCARBAZINE structure, PROCARBAZINE synthesis, PROCARBAZINE therapeutic uses

Procarbazine IUPAC nomenclature N-Isopropyl-4-[(2-methylhydrazino)methyl]benzamide Classification Procarbazine falls under the category of Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 221.3 g/mol 2 Appearance Present in solid form 3 Melting point 223°C 4 […]

HYDROXYUREA Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

February 9, 2020 GPAT Preparation, Study Material Chronic myeloid leukemia, Essential thrombocytosis, gpatindia, Head and neck cancer, Hydroxyurea, hydroxyurea chemical properties, hydroxyurea gpat questions, hydroxyurea gpatindia, hydroxyurea mechanism of action, hydroxyurea physical properties, hydroxyurea SAR, hydroxyurea side effects, hydroxyurea structure, hydroxyurea synthesis, hydroxyurea therapeutic uses, Melanoma, Polycythemia vera, Refractory ovarian cancer

Hydroxyurea IUPAC nomenclature Hydroxyurea Classification Hydroxurea falls under the category of Antineoplastic cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 76.055 g/mol 2 Appearance White to off-white crystalline solid 3 Melting point 141°C […]

ETOPOSIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

January 29, 2020 GPAT Preparation, Study Material etoposide, etoposide gpat question, etoposide iupac, etoposide mcq, etoposide mechanism of action, etoposide method of synthesis, etoposide SAR, etoposide side effects, etoposide structure, etoposide therapeutic uses, gpatindia, Structure Activity Relationship of Etoposide, Synthesis process Etoposide

Etoposide IUPAC nomenclature 4′-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside], 4′ -(dihydrogen phosphate). Classification Etoposide falls under the category of epipodophyllo toxin cytotoxic drug. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 588.6 g/mol 2 Appearance Present in solid form; crystal […]

IRINOTECAN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

January 27, 2020 GPAT Preparation, Study Material chiral center in Irinotecan, gpatindia, hair loss by irinotecan, irinotecan, Irinotecan binds with the topoisomerase I-DNA complex, irinotecan chemical properties, irinotecan gpat questions, irinotecan gpatindia, Irinotecan is used for metastatic colon cancer, Irinotecan is used for rectal cancer, irinotecan IUPAC, irinotecan mcq, irinotecan method of synthesis, irinotecan mode of action, irinotecan physical properties, irinotecan SAR, irinotecan side effects, irinotecan structure, irinotecan therapeutic uses, low blood count by Irinotecan, starting chemicals required for the synthesis of Irinotecan

Irinotecan IUPAC nomenclature (S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo1H-pyrano[3’,4’:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4’bipiperidine]-1’-carboxylate. Classification Irinotecan falls under the category of camptothecin cytotoxic drug. [1] Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 586.7g/mol 2 Appearance Pale yellow powder 3 Melting point Range between 222-223°C 4 Solubility […]

5-FLOUROURACIL (5-FU) Synthesis, SAR, MCQ,Structure,Therapeutic Uses, Chemical Property

January 9, 2020January 16, 2020 GPAT Preparation, MCQ, Study Material 5-flourouracil, 5-FU, 5-FU gpatindia, 5-FU gpatpreparation, 5-FU MCQs, 5-FU SAR, 5-FU side effects, 5-FU structure, 5-FU synthesis, 5-FU therapeutic effects, 5-FUmechanism of action, gpatindia

5-Fluorouracil (5-FU) IUPAC nomenclature 5-Fluoro-1H,3H-pyrimidine-2,4-dione Classification 5-Fluorouracil falls under the category of pyrimidine antagonist antimetabolite. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 130.08 g/mol 2 Appearance White crystalline powder 3 Melting point 283 °C 4 […]

CYTARABINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

January 9, 2020January 16, 2020 GPAT Preparation, Study Material cytarabine, Cytarabine adverse events, cytarabine chemical properties, cytarabine gpat, cytarabine gpatindia, cytarabine MCQs, cytarabine mechanism of action, cytarabine method of synthesis, cytarabine physical properties, cytarabine SAR, cytarabine side effects, cytarabine structure, cytarabine therapeutic effects, cytrabine iupac, gpatindia

Cytarabine IUPAC nomenclature 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5- (hydroxymethyl)oxolan-2-yl] pyrimidin-2-one Classification Cytarabine falls under the category of pyrimidine antagonist antimetabolite. Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 243.22 g/mol 2 Appearance Colorless crystalline powder 3 Melting point 212.5 °C 4 […]

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Tag: gpatindia

PREDNISOLONE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

CISPLATIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

CARBOPLATIN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

IMATINIB Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

PROCARBAZINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

HYDROXYUREA Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

ETOPOSIDE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

IRINOTECAN Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

5-FLOUROURACIL (5-FU) Synthesis, SAR, MCQ,Structure,Therapeutic Uses, Chemical Property

CYTARABINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses