Category: Medicinal Chemistry

TRIPROLIDINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Triprolidine IUPAC nomenclature 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl-prop-1-enyl]pyridine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 278.4 g/mol 2 Physical appearance Forms crystal from light petroleum 3 Melting point 60oC 4 Solubility 74.9 mg/LL 5 […]

Continue Reading

DIMETHINDENE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Dimethindene IUPAC nomenclature N,N-Dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethan-1-amine Classification H1-receptor antihistamine Alkylamine antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 292.4 g/mol 2 Physical appearance Solid 3 Melting point 158oC 4 Solubility 239 mg/LL 5 Octanol/water partition coefficient N/A […]

Continue Reading

DIMENHYDRINATE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Dimenhydrinate Chemical composition Diphenhydramine (53-55.5%) + 8-Chlorotheophylline (44-47%) IUPAC nomenclature 2-benzhydryloxy-N,N-dimethylethanamine;8-chloro-1,3-dimethyl-7H-purine-2,6-dione   Classification H1-receptor antihistamine Ethanolamine ether antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 470 g/mol 2 Physical appearance Crystalline white powder 3 Melting […]

Continue Reading

DOXYLAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Doxylamine IUPAC nomenclature (RS)-N,N-dimethyl-2-(1-phenyl-1-pyridin-2-yl-ethoxy)-ethanamine Classification H1-receptor antihistamine Ethanolamine ether antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 270.37 g/mol 2 Physical appearance Clear colorless liquid 3 Melting point <25oC 4 Solubility Soluble in acids 5 […]

Continue Reading

CLEMASTINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Clemastine IUPAC nomenclature  (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine Classification H1-receptor antihistamine Ethanolamine ether antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 343.9 g/mol 2 Physical appearance Solid 3 Melting point 178oC 4 Solubility Hydrogen fumarate formulation is soluble 5 […]

Continue Reading

BROMODIPHENHYDRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Bromazine Or Bromodiphenhydramine IUPAC nomenclature 2-[(4-Bromophenyl)-phenylmethoxy]-N,N-dimethylethanamine Classification H1-receptor antihistamine Ethanolamine ether antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 334.2 g/mol 2 Physical appearance Solid 3 Melting point 128-134oC 4 Solubility 3.45e-03 g/L 5 Octanol/water […]

Continue Reading

CARBINOXAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Carbinoxamine IUPAC nomenclature 2-[(4-Chlorophenyl)-pyridin-2-yl-methoxy]-N,N-dimethyl-ethanamine Classification H1-receptor antihistamine Ethanolamine ether antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 290.79 g/mol 2 Physical appearance Solid 3 Melting point <25oC 4 Solubility 2.28e-01 g/L 5 Octanol/water partition coefficient […]

Continue Reading

DIPHENHYYDRAMINE Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

Diphenhydramine IUPAC nomenclature 2-(diphenylmethoxy)-N,N-dimethylethanamine Classification H1-receptor antihistamine Diphenylmethane Ethanolamine ether antihistamine   Physiochemical Properties S. NO. PHYSICAL AND CHEMICAL PROPERTIES 1 Molecular weight 255.35 g/mol 2 Physical appearance Solid 3 Melting point 168oC 4 Solubility 3060 mg/L 5 Octanol/water partition […]

Continue Reading

ANTIVIRAL DRUGS Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses

ANTIVIRAL DRUGS ANTIVIRAL DRUGS Synthesis, SAR, MCQ,Structure,Chemical Properties and Therapeutic Uses Hydroxychloroquine click here Chloroquine click here Lopinavir click here Ritonavir click here Ivermectin click here Favipiravir click here Ribavirin click here Zanamivir click here Oseltamivir click here Peramivir click […]

Continue Reading

Developed By Connect Globes